Aims:As technology advances,concerns regarding neurobehavioral disorders,specifically memory deficits induced by electromagnetic radiation(EMR)from wireless devices like Wi-Fi routers have grown dramatically.This study aimed to investigate the impact of aerobic exercise on cholinergic biomarkers and amyloid beta(Aβ)levels in the hippocampus of male Wistar rats exposed to2450MHz EMR emitted by Wi-Fi routers.
Methods:Eighteen rats were randomly divided into three groups:'control','wave',and'wave+aerobic exercise'.During four weeks,the 'wave' groups were exposed to2450MHz EMR from Wi-Fi routers for four hours a day,seven days a week,while the 'wave+aerobic exercise' group underwent a running program for five days a week in addition to EMR exposure.Cognitive behavioral changes resulting from the interventions were evaluated using the Morris Water Maze (MWM) test.
Results:Exposure to EMR significantly decreased acetylcholine and acetylcholinesterase levels, and increased Aβ levels in the hippocampus(P<0.05).The MWM test also revealed a significant impairment in spatial memory among the exposed rats compared to the 'control' group.However,the 'wave+aerobic exercise' group exhibited a significant increase in acetylcholine and acetylcholinesterase levels, a significant reduction in Aβ levels, and demonstrated considerably better performance in the MWM test compared to the 'wave' group(P<0.05).
Conclusion:The findings of this study demonstrate the beneficial effects of aerobic exercise in preventing pathophysiological alterations and cognitive impairments caused by electromagnetic radiation.
Esmaeili, M. , Pournemati, P. , Shabkhiz, F. and Kordi, M. (2025). Aerobic exercise prevents memory deficits caused by electromagnetic radiation through modifying cholinergic biomarkers and amyloid beta. Sport Sciences and Health Research, 17(2), 12-29. doi: 10.22059/sshr.2025.381752.1161
MLA
Esmaeili, M. , , Pournemati, P. , , Shabkhiz, F. , and Kordi, M. . "Aerobic exercise prevents memory deficits caused by electromagnetic radiation through modifying cholinergic biomarkers and amyloid beta", Sport Sciences and Health Research, 17, 2, 2025, 12-29. doi: 10.22059/sshr.2025.381752.1161
HARVARD
Esmaeili, M., Pournemati, P., Shabkhiz, F., Kordi, M. (2025). 'Aerobic exercise prevents memory deficits caused by electromagnetic radiation through modifying cholinergic biomarkers and amyloid beta', Sport Sciences and Health Research, 17(2), pp. 12-29. doi: 10.22059/sshr.2025.381752.1161
CHICAGO
M. Esmaeili , P. Pournemati , F. Shabkhiz and M. Kordi, "Aerobic exercise prevents memory deficits caused by electromagnetic radiation through modifying cholinergic biomarkers and amyloid beta," Sport Sciences and Health Research, 17 2 (2025): 12-29, doi: 10.22059/sshr.2025.381752.1161
VANCOUVER
Esmaeili, M., Pournemati, P., Shabkhiz, F., Kordi, M. Aerobic exercise prevents memory deficits caused by electromagnetic radiation through modifying cholinergic biomarkers and amyloid beta. Sport Sciences and Health Research, 2025; 17(2): 12-29. doi: 10.22059/sshr.2025.381752.1161
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